Floating Elementary Osmotic Pump Tablet (FEOPT) for Controlled Delivery of Diethylcarbamazine Citrate: a Water-Soluble Drug
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منابع مشابه
Novel osmotic pump tablet using core of drug-resin complexes for time-controlled delivery system.
A novel elementary osmotic pump tablet was developed. The system uses the core of drug-resin complexes (DRCs) loaded with propranolol hydrochloride (PNH) for time-controlled delivery. In traditional osmotic pump tablets (OPTs), the lag time was always minimized. However, in the DRCs osmotic pump tablet (DRCOPT), the lag time was increased to achieve the time-controlled delivery. The quantity of...
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The main intention of the present work is to design and evaluate a new Elementary Osmotic Pump (EOP) for efficient delivery of Poorly Water-Soluble Drugs (PWSDs). Drug release from the new system called Expandable EOP (EEOP), is through a porous semipermeable membrane in the form of a suspension ready for dissolution and absorption. EEOP tablets were prepared by compressing the mixture of drug ...
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Conventional drug delivery systems have little control over their drug release and almost no control over the effective concentration at the target site. The major problem associated with conventional drug delivery system is unpredictable plasma concentrations. Osmotic devices are the most promising strategy based systems for controlled drug delivery. They are the most reliable controlled drug ...
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The present study was to prepare a gastro retentive drug delivery system of Losartan floating tablets, was designed to increase the gastric residence time, thus prolong the drug release. The different type formulations were prepared by using polymers like HPMC K100M, ethyl cellulose, talc and lactose. In the present study Sodium bicarbonate and citric acid were incorporated as a gas generating ...
متن کاملOsmotic Controlled Drug Delivery System: A Review
Department of Pharmaceutics, Hindu College of Pharmacy, Guntur, Andhra Pradesh, India. _______________________________________________________________________ ABSTRACT Conventional drug delivery systems have slight control over their drug release and almost no control over the effective concentration at the target site. This kind of dosing pattern may result in constantly changing, unpredictabl...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2011
ISSN: 1530-9932
DOI: 10.1208/s12249-011-9699-6